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Yasushi Hirota Selected Research

ONO 6818

2/2005Pathophysiological studies of trinitrobenzene sulfonic acid-induced colitis in Syrian hamsters (Mesocricetus auratus).
10/2004Effects of the neutrophil elastase inhibitor (ONO-6818) on acetic acid induced colitis in Syrian hamsters.

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Yasushi Hirota Research Topics

Disease

57Endometriosis
12/2022 - 07/2003
18Inflammation (Inflammations)
10/2023 - 05/2003
11Adenomyosis
11/2023 - 10/2014
8Neoplasms (Cancer)
12/2023 - 04/2005
6Infertility (Sterility)
08/2023 - 01/2016
6Pre-Eclampsia (Preeclampsia)
11/2019 - 05/2003
5Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal)
01/2024 - 01/2019
4Fibrosis (Cirrhosis)
07/2019 - 10/2005
4Premature Birth (Birth, Premature)
09/2013 - 03/2010
4Colitis
08/2005 - 04/2004
3Hyperandrogenism
04/2024 - 01/2019
3Hypoxia (Hypoxemia)
02/2024 - 10/2003
3Leiomyoma (Uterine Fibroids)
12/2022 - 12/2005
3Hemorrhage
10/2020 - 10/2012
3Ulcer
02/2005 - 04/2004
2Polyps
10/2023 - 01/2020
2Dysmenorrhea (Menstrual Pain)
01/2023 - 12/2022
2Obesity
01/2021 - 01/2017
2Uterine Hemorrhage (Uterine Bleeding)
10/2020 - 09/2020
2Anemia
10/2020 - 10/2014
2Pneumothorax
06/2018 - 09/2015
2Endometrial Neoplasms (Endometrial Cancer)
07/2006 - 12/2005
1Retinoblastoma (Glioblastoma, Retinal)
02/2024
1Primary Ovarian Insufficiency
12/2023
1Menorrhagia
01/2023
1Dysbiosis
11/2021

Drug/Important Bio-Agent (IBA)

9dienogestFDA Link
12/2022 - 05/2008
8Proteins (Proteins, Gene)FDA Link
01/2020 - 11/2005
7EnzymesIBA
01/2020 - 10/2004
6CytokinesIBA
01/2020 - 08/2008
6Progestins (Progestagens)IBA
01/2020 - 03/2013
5Gonadotropin-Releasing Hormone (GnRH)FDA Link
10/2023 - 04/2005
5Estrogens (Estrogen)FDA Link
12/2022 - 12/2005
5Messenger RNA (mRNA)IBA
01/2021 - 11/2005
5Interleukin-8 (Interleukin 8)IBA
11/2014 - 10/2003
5InterleukinsIBA
11/2012 - 10/2003
4ProgesteroneFDA LinkGeneric
01/2020 - 12/2008
4Proteinase-Activated ReceptorsIBA
01/2012 - 06/2005
4AdiponectinIBA
02/2007 - 10/2005
4Leukocyte Elastase (Neutrophil Elastase)IBA
08/2005 - 04/2004
3Progesterone Receptors (Progesterone Receptor)IBA
02/2024 - 09/2014
3AndrogensIBA
01/2024 - 01/2020
3Hemoglobins (Hemoglobin)IBA
01/2023 - 10/2004
3Hormones (Hormone)IBA
12/2022 - 07/2009
3Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2021 - 05/2003
3Aromatase (CYP19)IBA
12/2016 - 04/2013
3Mechanistic Target of Rapamycin Complex 1IBA
01/2016 - 11/2011
3Interleukin-6 (Interleukin 6)IBA
11/2014 - 07/2011
3Interleukin-4 (Interleukin 4)IBA
04/2013 - 08/2008
3Interleukin-17 (Interleukin 17)IBA
11/2012 - 03/2008
3Vascular Endothelial Growth Factor Receptor-1 (fms-Like Tyrosine Kinase)IBA
10/2012 - 05/2003
3ThrombinFDA Link
10/2012 - 08/2003
3Phenobarbital (Luminal)FDA Link
08/2005 - 04/2004
3Peroxidase (Myeloperoxidase)IBA
02/2005 - 04/2004
2Levonorgestrel (Plan B)FDA LinkGeneric
01/2023 - 01/2020
2Mitogen-Activated Protein KinasesIBA
11/2022 - 11/2004
2ChemokinesIBA
01/2021 - 07/2003
2LigandsIBA
01/2021 - 02/2009
2InterferonsIBA
01/2020 - 02/2019
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020 - 01/2017
2AntralIBA
11/2019 - 01/2019
2Oral ContraceptivesIBA
10/2019 - 01/2017
2Therapeutic UsesIBA
12/2016 - 09/2014
2ResveratrolIBA
04/2016 - 01/2016
2Metformin (Glucophage)FDA LinkGeneric
01/2016 - 08/2007
2Sirolimus (Rapamycin)FDA Link
09/2013 - 11/2011
2activin AIBA
06/2013 - 07/2011
2ImmunosorbentsIBA
06/2013 - 10/2005
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2011 - 02/2009
2OsteoprotegerinIBA
02/2009 - 10/2004
2Estradiol (Delestrogen)FDA LinkGeneric
08/2007 - 12/2006
2p38 Mitogen-Activated Protein KinasesIBA
12/2006 - 11/2004
2N 30IBA
12/2005 - 04/2005
2Sulfonic AcidsIBA
08/2005 - 02/2005
2ONO 6818IBA
02/2005 - 10/2004
2Prednisolone (Predate)FDA LinkGeneric
02/2005 - 04/2004
2Acetic Acid (Vinegar)FDA LinkGeneric
10/2004 - 04/2004
1Testosterone (Sustanon)FDA Link
04/2024
1Nuclear Proteins (Protein, Nuclear)IBA
02/2024
1Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2023
1Tacrolimus (Prograf)FDA LinkGeneric
08/2023
1EkoIBA
01/2023
1Estrogen ReceptorsIBA
11/2022
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2022
1Diphtheria ToxinIBA
01/2021
1Endocrine DisruptorsIBA
01/2021
1Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2021
1Prostaglandin E Receptors (Prostaglandin E Receptor)IBA
01/2021
1ProstaglandinsIBA
01/2021
1Heparin-binding EGF-like Growth Factor (HB-EGF)IBA
01/2021

Therapy/Procedure

7Therapeutics
12/2022 - 08/2007
5Hysterectomy
11/2022 - 07/2015
2Laparotomy
11/2023 - 11/2012
2Oral Administration
09/2020 - 03/2010
2Cystectomy
01/2019 - 07/2015
2Cesarean Section (Caesarean Section)
02/2017 - 06/2005
1Drug Therapy (Chemotherapy)
12/2023
1Uterine Myomectomy
10/2023
1Intraperitoneal Injections
10/2022
1Conservative Treatment
07/2022